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Machine learning models for biomarker and clinical data

Diagnostic and prognostic models you can explain, with honest performance estimates instead of numbers inflated by data leakage.

Who it's for

What you receive

AI and machine learning models

You receive: Feature selection, nested cross-validation, honest performance on held-out data, and explanations of which features drive each prediction, following TRIPOD standards.

Data we accept

Expression matrices, qPCR panels or clinical tables in Excel, CSV or SPSS, with the outcome you want to predict. We work with anonymised data only, and a confidentiality agreement can be signed before you share anything.

How a project runs

Analysis, figures and tables only; manuscript writing is not included.

Questions

Why nested cross-validation?
Choosing features and tuning a model on the same data used to measure it makes performance look better than it is. Nested cross-validation keeps those steps separate.
Will I know why the model makes its predictions?
Yes. SHAP values and model coefficients show which features drive each prediction, overall and for individual samples.
Is a small dataset enough?
Often, with the right model and validation. The analysis plan states what your sample size can and cannot support before work starts.

Tell us about your project

Share your study and the data you have. You'll receive an analysis plan and a fixed quote before any work starts.

Request a quote

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